目的 研究米酒对瓜蒌薤白中主要活性成分3，29-二苯甲酰基栝楼仁三醇在人肠道菌群中代谢的影响，从代谢角度探讨瓜蒌薤白白酒汤的科学内涵。方法 通过肠道菌群试验比较不同时间点瓜蒌薤白米酒溶液和水溶液中3，29-二苯甲酰基栝楼仁三醇的代谢率。结果 与瓜蒌薤白水溶液组相比，瓜蒌薤白米酒溶液组中3，29-二苯甲酰基栝楼仁三醇的代谢率明显降低(P<0.05)。结论 米酒可抑制瓜蒌薤白中3，29-二苯甲酰基栝楼仁三醇的代谢。
Abstract
OBJECTIVE To study the effects of rice wine on the metabolism of 3,29- dibenzoyl karounitriol as the main active component in Gualou-Xiebai in human intestinal flora, exploring the scientific connotation of Gualou-XiebaiBaijiu Decoction from the angle of metabolism.METHODS The metabolic rate of 3,29-dibenzoyl karounitriol in Gualou-Xiebai rice wine solution and aqueous solution at different time points were compared, respectively, by intestinal flora experiments.RESULTS Compared to Gualou-Xiebaiaqueous solution group,the metabolic rate of 3,29-dibenzoyl karounitriol in Gualou-Xiebai rice wine solution group decreased significantly (P<0.05 ). CONCLUSION Rice wine as cites drug can inhibit the metabolism of 3,29- dibenzoyl karounitriol in Gualou-Xiebai.
关键词
引药 /
米酒 /
肠道菌群
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Key words
cites drug /
rice wine /
intestinal flora
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中图分类号：
R969.1
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参考文献
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脚注
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基金
安徽高校省级自然科学研究重大项目(KJ2015ZD41,KJ2016SD60);安徽省科技攻关项目(12010402089);国家大学生创新创业训练计划项目(201510368018)
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